Endocrine Abstracts

Background: In patients with acromegaly, mortality depends most on achievement of control of GH/IGF1 levels. However, some of the complications of acromegaly still develop, despite successful control of disease. The aim of the study is to correlate mortality and morbidity with cumulative GH exposure in these patients compared to last GH/IGF1 level.Methods: We studied retrospectively 336 patients with acromegaly consecutively evaluated at least twice duri...

Background and aims: Patients with GH secreting or nonfunctioning pituitary adenoma (NFPA) have high mortality ratios, despite enhancement of the old therapies. The aim of the study is to analyze the relationship between mortality and risk factors, including therapy, in patients with acromegaly (ACM) and NFPA evaluated in the last 16 years.Methods: We evaluated retrospectively 749 patients with pituitary adenoma (435F/314M), 386 with ACM and 363 with NFP...

Introduction: Acromegaly has various complications that significantly alter patients’ lives, one of which is developing neoplasia, a subject of high interest in the scientific community during the last years but without any firm conclusions.Aim: The main objective of this paper was to verify if Romanian acromegalic patients are susceptible to developing neoplasia and what types of tumors are associated with acromegaly. Another purpose of the paper w...

Objective: Patients with pituitary macroadenomas and concomitant hypopituitarism have a reduced life expectancy due to various comorbidities.Aim: To investigate mortality in patients with non-functioning pituitary adenomas (NFAs) and independent prognostic factors influencing survival.Design: Retrospective cohort study in a tertiary neuroendocrine university department.Methods: A total of 364 patients (177F/1...